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Gastroenterology

News, opinions and meeting coverage in gastroenterology.

Novel Drug Effective Against MASH in Phase II Trial

— Fatty acid synthase inhibitor targets main drivers of liver injury

 A computer rendering of a diseased liver in a transparent body.

Latest in Gastroenterology

Highest Paid Medical 51˶ in 2024

Each of these specialties average over $500k per year

Oct 10, 2024
Some Cancers Occur More Frequently in Multiple Sclerosis Patients

Bladder, brain, and cervical cancer risks were higher in people with MS

Oct 09, 2024
Colorectal Cancer Screening Uptake Tripled in 45-49 Age Group

Rates rose after USPSTF recommendation, but increase was uneven

Oct 03, 2024
Some Cancers Occur More Frequently in Multiple Sclerosis Patients

Bladder, brain, and cervical cancer risks were higher in people with MS

Colorectal Cancer Screening Uptake Tripled in 45-49 Age Group

Rates rose after USPSTF recommendation, but increase was uneven

Gastroenterology Case Studies

Child Develops Voluminous Diarrhea After Amoxicillin

Discordant test results complicate diagnosis of suspected C. difficile

 A photo of a fecal sample container.
Elderly Farmer Experiences Strange Abdominal Rash and GI Symptoms

Moral of the story: don't walk barefoot in the fields

A photo of a senior woman laying in bed grimacing and holding her stomach.
Case Shows Danger of Gallstone Ileus in Patients Over 65

Clinicians found CT scan to be best diagnostic tool

 A photo of a senior woman outdoors doubled over in pain.

More in Gastroenterology

What Skin Says About Health

Knowing what to look for can mean the difference between life and death

Oct 03, 2024
The YouTube thumbnail with Siobhan Deshauer, MD, a photo of skin tags, and the words: HIGH SUGAR.
Food Retention Risk Low for GLP-1 Users When Endoscopy Is Combined With Colonoscopy

Bowel preparation protocols appeared protective in small study

Oct 01, 2024
A photo of male and female healthcare workers performing an endoscopy on a female patient.
H. Pylori Testing Did Not Reduce Gastric Cancer Incidence, Mortality

Gastric cancer incidence was lower after adjusting for certain factors in post hoc analyses

Sep 30, 2024
A photo of a stool collection container.
No Benefit for PD-1 Inhibitors in Certain Gastroesophageal Cancers, FDA Panel Says

Despite problematic dataset, risk/benefit profile not favorable with PD-L1 expression below 1

Sep 27, 2024
 FDA ODAC PD-(L)1 inhibitors over a computer rendering of esophageal cancer
Placebos Linked to Potential Harms in IBD Clinical Trials

Alternative designs needed, researchers caution

Sep 26, 2024
A photo of a white tablet lying on top of many pink tablets.
Timely Skin Cancer Screening After Organ Transplant Still Lacking

Only a minority of patients adhered to SUNTRAC screening recommendations

Sep 26, 2024
The SUNTRAC logo next to a screenshot of the web application.
Novel Monoclonal Antibody Shows Promise in Ulcerative Colitis

26% of patients receiving tulisokibart achieved clinical remission vs 1% with placebo

Sep 25, 2024
A computer rendering of monoclonal antibodies.
Immunotherapy May Not Benefit All Gastroesophageal Cancer Patients, FDA Staff Says

Data since approvals suggest benefits limited to subgroups with PD-L1 expression of at least 1%

Sep 24, 2024
FDA ODAC PD-(L)1 inhibitors over a computer rendering of esophageal cancer
FDA Rejects NK1R Antagonist for Gastroparesis

Drugmaker none-too-pleased with agency's request for additional studies

Sep 19, 2024
FDA CRL tradipitant (Vanda) over a computer rendering of a stomach.
GLP-1 Drugs in MASLD Tied to Lower Risk of Cirrhosis, Death

Limited benefit seen in patients with established cirrhosis, however

Sep 16, 2024
A close up photo of an injection pen.
Another Possible Treatment Option for Intermediate-Stage Liver Cancer

Adding lenvatinib, pembrolizumab to TACE significantly improved PFS, numerically improved OS

Sep 16, 2024
ESMO over a photo of Fira Barcelona Gran Via in Barcelona, Spain.
Approved Liver Disease Drug Has No Clinical Benefit, FDA Panel Says

Agency advisors put their foot down on shaky science for Ocaliva in primary biliary cholangitis

Sep 13, 2024
FDA ADCOMM obeticholic acid (Ocaliva) over a computer rendering of a liver with the biliary tree highlighted.
HHS Proposes Rule to Increase Access to Kidney, Liver Transplants in HIV Patients

Rule would streamline criteria for organ donation from donors with HIV to recipients with HIV

Sep 13, 2024
A photo of surgeons performing a kidney transplant.
FDA Warning on Hot Flash Drug

Clinicians should perform liver blood tests before and during Veozah treatment

Sep 12, 2024
FDA WARNING fezolinetant (Veozah) over a photo of Veozah tablet, bottle and packaging.
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